Prednisolone

From DrugPedia: A Wikipedia for Drug discovery

[edit] Description

Show 3-D Structure

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

[edit] General Properties

*Molecular Weight

360.44

*Molecular Formula

C₂₁H₂₈O₅

*IUPAC NAME

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O

*Isomeric Smiles

C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O

[edit] PhysioChemical Properties

*Melting Point

235(EXP)

*LogP

1.62(EXP)

*Water Solubility

223(EXP) at 25C

[edit] External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]KEGG Drug
• [4]Drugbank