17-alpha-Hydroxyprogesterone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. Show 3-D Structure

General Properties

*Molecular Weight

330.46

*Molecular Formula

C₂₁H₃₀O₃

*IUPAC NAME

(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O

*Isomeric Smiles

CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

PhysioChemical Properties

*Melting Point

222-223(EXP)

*LogP

3.17(EXP)

*Water Solubility

6.48(EXP) at 27C

External Links

• [1]Pubchem
• [2]]KEGG Compound
• [3]Human Metabolome DataBase

Categories:Hormones