Gastrin-16
From DrugPedia: A Wikipedia for Drug discovery
Contents |
Description
Gastrin precursor [Contains: Big gastrin (Gastrin-33); Gastrin-16;Gastrin-15].
Source Organism
Macropus giganteus (Eastern gray kangaroo).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular Localization
Secreted.
Developmental Stage
Similarity
Belongs to the gastrin/cholecystokinin family.
Post translational Modification
Function
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
