Muellerian-inhibiting factor

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 Source Organism 3 Taxomomy 4 Subcellular Localization 5 Developmental Stage 6 Similarity 7 Post translational Modification 8 Function 9 GeneID

[edit] Description

Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone)(AMH) (Muellerian-inhibiting substance).

[edit] Source Organism

Bos taurus (Bovine).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.

[edit] Subcellular Localization

Secreted protein.

[edit] Developmental Stage

[edit] Similarity

Belongs to the TGF-beta family.

[edit] Post translational Modification

[edit] Function

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin

[edit] GeneID

280718