Androstenediol

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

General Properties

*Molecular Weight

290.44

*Molecular Formula

C₁₉H₃₀O₂

*IUPAC NAME

(3S,8R,9S,10R,13S,14S,17S)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol

*Canonical Smiles

CC12CCC3C(C1CCC2O)CC=C4C3(CCC(C4)O)C

*Isomeric Smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC=C4[C@@]3(CC[C@@H](C4)O)C

PhysioChemical Properties

*Melting Point

*LogP

4.58(EST)

*Water Solubility

External Links

• [1]Pubchem
• [2]]KEGG Compound
• [3]]KEGG Drug
• [4]Human Metabolome DataBase

Categories:Hormones