Aldosterone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

General Properties

*Molecular Weight

360.44

*Molecular Formula

C₂₁H₂₈O₅

*IUPAC NAME

(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde

*Canonical Smiles

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C=O)O

*Isomeric Smiles

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C=O)O

PhysioChemical Properties

*Melting Point

166.5(EXP)

*LogP

1.08(EXP)

*Water Solubility

51.2(EXP) at 37C

External Links

• [1]Pubchem
• [2]]KEGG Compound
• [3]Human Metabolome DataBase
• [4]Drugbank

Categories:Hormones