CarboDB Lipopolysaccharide 1092

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Actinobacillus pleuropneumoniae

[edit] Basic Structure

O chains of LPS of serotypes 4 and 7 were structurally similar, being composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone

[edit] Proposed functions

LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus

[edit] Antigenic Nature used to produce antibodies

whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

2Mab5

[edit] Antibody type and class

IgG2a

[edit] Assay System

Elisa inhibition assay

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

O-antigenic polysaccharide moeity inside the LPS. The epitope was proposed to include O-acetyl group of C6 position of glucose in the middle of repeating units

[edit] Proposed Utility

N/A

[edit] Weblink

PubMed

[edit] External Links

• Link to CarboDB database