From DrugPedia: A Wikipedia for Drug discovery

Immunotation of Rv2753c (dihydrodipicolinate synthase)
Name
Dihydrodipicolinate Synthase
Identifiers
Swiss Prot	P63945
Genbank	888289
PDB	1XXX
Chemical data
Formula	?
Mol. wt.	30,858 Da
Pharmacokinetic data
Bioavailability	?
Solubility	?
Isoelectric-Point	5.57

Contents 1 General 2 Antigens 3 Haptens 4 Epitopes 4.1 B-Cell Epitopes 4.2 MHC class I restricted T cell epitopes 4.3 CTL Epitopes 5 MHC Binder 5.1 Class-I Binder 5.2 Class-II Binder 6 TAP Binder 7 Alergen Protein 8 Antibacterial 9 Bacterial Toxin 10 External Links

General

dapA catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate.

L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2H₂O.

This protein is eesential for optimal growth of M.tb and found in the cytoplasm as predicted by the WoLFPSORT and Subloc Server. HMMpfam found one domain PF00701 and has Helix Turn Helix secondary structure.

Antigens

Haptens

Epitopes

B-Cell Epitopes

MHC class I restricted T cell epitopes

CTL Epitopes

MHC Binder

Class-I Binder

Class-II Binder

TAP Binder

Alergen Protein

Antibacterial

Bacterial Toxin

External Links