Capaurine
From DrugPedia: A Wikipedia for Drug discovery
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| PubChem = 94149 | | PubChem = 94149 | ||
| DrugBank = | | DrugBank = | ||
| - | | ChemSpiderID = | + | | ChemSpiderID = 84966 |
| chemical_formula =C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>5</sub>NO<sub>5</sub> | | chemical_formula =C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>5</sub>NO<sub>5</sub> | ||
| molecular_weight = 371.4269 | | molecular_weight = 371.4269 | ||
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60.4 | 60.4 | ||
| + | ==Source== | ||
| + | Anomianthus dulcis | ||
| + | |||
| + | Corydalis aurea | ||
| + | |||
| + | Corydalis micrantha | ||
| + | |||
| + | Corydalis montana | ||
| + | |||
| + | Corydalis pallida | ||
| + | |||
| + | Stephania lincangensis | ||
| + | |||
| + | ==Function== | ||
| + | uterine stimulant activity | ||
| + | |||
| + | ==Toxicity== | ||
| + | Organism Test Type Route Reported Dose (Normalized Dose) Effect Source | ||
| + | |||
| + | mouse LD50 intravenous 56mg/kg (56mg/kg) Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 5, Pg. 163, 1946. | ||
==External Links== | ==External Links== | ||
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[http://crdd.osdd.net/raghava/biadb/detail.php?id=2127 Link to BIAdb Database] | [http://crdd.osdd.net/raghava/biadb/detail.php?id=2127 Link to BIAdb Database] | ||
| + | |||
| + | ==Reference== | ||
| + | Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter21 | ||
Revision as of 04:29, 4 May 2009
| Capaurine
| |
| Systematic (IUPAC) name | |
| (13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C21H25NO5 |
| Mol. mass | 371.4269 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Contents |
Description
from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (S)-isomer
General Properties
*Molecular Weight
371.4269
*Molecular Formula
C21H25NO5
*IUPAC NAME
(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol
*Canonical Smiles
COC1=C(C2=C(CC3C4=C(C(=C(C=C4CCN3C2)OC)OC)O)C=C1)OC
*Isomeric Smiles
COC1=C(C2=C(C[C@H]3C4=C(C(=C(C=C4CCN3C2)OC)OC)O)C=C1)OC
*XLogP
2
*Topological Polar Surface Area
60.4
Source
Anomianthus dulcis
Corydalis aurea
Corydalis micrantha
Corydalis montana
Corydalis pallida
Stephania lincangensis
Function
uterine stimulant activity
Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 56mg/kg (56mg/kg) Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 5, Pg. 163, 1946.
External Links
Reference
Harborne,Phytochemical Dictionary Second Edition,Taylor and Francis,(1999),Chapter21
