Diquafosol
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
purinoceptor P2Y(2) receptor agonist | purinoceptor P2Y(2) receptor agonist | ||
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| + | Diquafosol stimulates the eye surface cells directly to promote secretion of fluid and mucin and possibly stimulates lipid production in the meibomian glands as well. Because diquafosol stimulates fluid and mucin secretion directly on the ocular surface, it is believed to provide moisture and rehydration of the ocular surface independent of tear film secretion from the lacrimal gland. | ||
==General Properties== | ==General Properties== | ||
Revision as of 08:41, 2 May 2009
{{Drugbox | IUPAC_name =tetrasodium[[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxy-oxidophosphoryl][(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate | PubChem = 148196 | DrugBank = | ChemSpiderID = | chemical_formula =C18H22N4Na4O23P4 | molecular_weight = 878.234404 | smiles = C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O.[Na+].[Na+].[Na+].[Na+] | synonyms = | density = | melting_point = | boiling_point = | solubility = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = }}
Description
purinoceptor P2Y(2) receptor agonist
Diquafosol stimulates the eye surface cells directly to promote secretion of fluid and mucin and possibly stimulates lipid production in the meibomian glands as well. Because diquafosol stimulates fluid and mucin secretion directly on the ocular surface, it is believed to provide moisture and rehydration of the ocular surface independent of tear film secretion from the lacrimal gland.
General Properties
*Molecular Weight
878.234404
*Molecular Formula
C18H22N4Na4O23P4
*IUPAC NAME
tetrasodium[[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxy-oxidophosphoryl][(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
*Canonical Smiles
C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O)O.[Na+].[Na+].[Na+].[Na+]
*Isomeric Smiles
C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O.[Na+].[Na+].[Na+].[Na+]
*XLogP
N/A
*Topological Polar Surface Area
405
