Norepinephrine
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic. | Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic. | ||
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| + | As a [[stress hormone]], norepinephrine affects parts of the brain where [[attention]] and responding actions are controlled. Along with [[epinephrine]], norepinephrine also underlies the [[fight-or-flight response]], directly increasing [[heart rate]], triggering the release of [[glucose]] from energy stores, and increasing blood flow to [[skeletal muscle]]. | ||
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==General Properties== | ==General Properties== | ||
Revision as of 07:02, 17 February 2009
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Contents |
Description
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
As a stress hormone, norepinephrine affects parts of the brain where attention and responding actions are controlled. Along with epinephrine, norepinephrine also underlies the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle.
General Properties
*Molecular Weight
169.18
*Molecular Formula
C8H11NO3
*IUPAC NAME
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
*Canonical Smiles
C1=CC(=C(C=C1C(CN)O)O)O
*Isomeric Smiles
C1=CC(=C(C=C1[C@H](CN)O)O)O
PhysioChemical Properties
*Melting Point
*LogP
*Water Solubility
