Retinoic acid receptor delta;RAR-delta
From DrugPedia: A Wikipedia for Drug discovery
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Revision as of 00:00, 15 January 2001
Contents |
Source Organism
Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Caudata; Salamandroidea; Salamandridae;Notophthalmus.
Subcellular Localization
Nucleus.
Developmental Stage
Similarity
Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post translational Modification
Function
This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.