Protein tailless homolog;Tll;hTll
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
Revision as of 00:00, 15 January 2001
Contents |
Source Organism
Homo sapiens (Human).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular Localization
Nucleus (By similarity).
Developmental Stage
Similarity
Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post translational Modification
Function
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).
