Hormone receptor 4

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Revision as of 07:57, 13 February 2009

Contents

Source Organism

Drosophila melanogaster (Fruit fly).

Taxomomy

Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.

Subcellular Localization

Nucleus.

Developmental Stage

Similarity

Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.

Post translational Modification

Function

Coordinates growth and maturation by mediating endocrine responses to the attainment of critical weight during larval development. Plays a central role in the genetic cascades triggered by the steroid hormone ecdysone at the onset of metamorphosis, acting as both a repressor of the early ecdysone- induced regulatory genes and an inducer of the ftz-f1 midprepupal competence factor.

Categories:Receptors