Leukotriene B4

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)

General Properties

*Molecular Weight

336.47

*Molecular Formula

C₂₀H₃₂O₄

*IUPAC NAME

(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid

*Canonical Smiles

CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O

*Isomeric Smiles

CCCCCC=C/C[C@H](C=CC=CC=C/[C@H](CCCC(=O)O)O)O

PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Human Metabolome DataBase

Categories:Hormones