Mechanistic Toxicology

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(New page: ==definition== Is a branch of Toxicology, which focuses on * Chemicals produce adverse effects * Biological systems protect themselves against adverse effects Chemical research in toxicolo...)
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==definition==
==definition==
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Is a branch of Toxicology, which focuses on
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Is a branch of [[Toxicology]], which focuses on
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* Chemicals produce adverse effects
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* [[Chemicals]] produce adverse effects
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* Biological systems protect themselves against adverse effects
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* [[Biological]] systems protect themselves against adverse effects
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Chemical research in toxicology usually investigates metabolic transformations of drugs or potentially hazardous chemicals.
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Chemical research in [[toxicology]] usually investigates metabolic transformations of drugs or potentially hazardous chemicals.
'''Involves'''
'''Involves'''
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* How persistent is a chemical in the body?
* How persistent is a chemical in the body?
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* Are metabolic products toxic?
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* Are [[metabolic]] products toxic?
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* Do test animals exhibit the same results as humans or other species of concern?
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* Do test animals exhibit the same results as humans or other [[species]] of concern?

Revision as of 09:47, 11 August 2008

definition

Is a branch of Toxicology, which focuses on

  • Chemicals produce adverse effects
  • Biological systems protect themselves against adverse effects

Chemical research in toxicology usually investigates metabolic transformations of drugs or potentially hazardous chemicals.

Involves

  • Cellular and Molecular Biology
  • Chemistry, often xenobiotic metabolism

Questions asked by Mechanistic Toxicologist

  • How persistent is a chemical in the body?
  • Are metabolic products toxic?
  • Do test animals exhibit the same results as humans or other species of concern?