Diflucortolone

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Revision as of 07:10, 13 February 2009

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A topical glucocorticoid used in various DERMATOSES. It is absorbed through the skin, bound to plasma albumin, and may cause adrenal suppression. It is also administered as the valerate.

General Properties

*Molecular Weight

394.45

*Molecular Formula

C₂₂H₂₈F₂O₄

*IUPAC NAME

(6S,9R,16R)-6,9-difluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1C(=O)CO)C)O)F)C)F

*Isomeric Smiles

C[C@@H]1CC2C3C[C@@H](C4=CC(=O)C=CC4([C@]3(C(CC2(C1C(=O)CO)C)O)F)C)F

PhysioChemical Properties

*Melting Point

242(EXP)

*LogP

1.96(EST)

*Water Solubility

External Links

• [1]Pubchem

Categories:Hormones