Mechanistic Toxicology
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Revision as of 09:43, 11 August 2008
definition
Is a branch of Toxicology, which focuses on
- Chemicals produce adverse effects
- Biological systems protect themselves against adverse effects
Chemical research in toxicology usually investigates metabolic transformations of drugs or potentially hazardous chemicals.
Involves
- Cellular and Molecular Biology
- Chemistry, often xenobiotic metabolism
Questions asked by Mechanistic Toxicologist
- How persistent is a chemical in the body?
- Are metabolic products toxic?
- Do test animals exhibit the same results as humans or other species of concern?