Desoxycorticosterone

(Difference between revisions)

Revision as of 00:00, 15 January 2001

21-Hydroxypregn-4-ene-3,20-dione. Desoxycorticosterone acetate (DOCA) is used as replacement therapy in ADDISON DISEASE.

*Molecular Weight

330.46

*Molecular Formula

C₂₁H₃₀O₃

*IUPAC NAME

(8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C

*Isomeric Smiles

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)CO)CCC4=CC(=O)CC[C@]34C

*Melting Point

141.5(EXP)

*LogP

2.88(EXP)

*Water Solubility

59.5(EXP) at 37C