Dihydrotestosterone

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Revision as of 07:10, 13 February 2009

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A potent androgenic metabolite of TESTOSTERONE. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to ESTRADIOL therefore DHT is considered a pure androgenic steroid.

General Properties

*Molecular Weight

290.44

*Molecular Formula

C₁₉H₃₀O₂

*IUPAC NAME

(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CCC(=O)CC1CCC3C2CCC4(C3CCC4O)C

*Isomeric Smiles

C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C

PhysioChemical Properties

*Melting Point

181(EXP)

*LogP

3.55(EXP)

*Water Solubility

5.25E+05(EXP) at 25C

External Links

• [1]Pubchem
• [2]]1D2S,[[3]]1F5F,[[4]]1KDK,[[5]]1KDM,[[6]]1T73,[[7]]1T74,[[8]]1T76,[[9]]1T79,[[10]]1T7F,[[11]]1T7M,[[12]]1T7R,[[13]]1T7T,[[14]]1T5Z,[[15]]1T63,[[16]]1T65,[[17]]1XJ7,[[18]]2AMA,[[19]]2PIO,[[20]]2PIP,[[21]]2PIQ,[[22]]2PIR,[[23]]2PIT,[[24]]2PIU,[[25]]2PIV,[[26]]2PIW,[[27]]2PIX,[[28]]2PKL,[[29]]2QPY,[[30]]2Z4J,
• [31]]KEGG Compound
• [32]]KEGG Drug
• [33]Human Metabolome DataBase
• [34]Drugbank

Categories:Hormones