5alpha-Dihydroprogesterone
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
m (New page: 3,20-Allopregnanedione Pubchem(92810) A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREG...) |
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KEGG Pathway(C03681) | KEGG Pathway(C03681) | ||
C21-Steroid hormone metabolism | C21-Steroid hormone metabolism | ||
| - | + | {| border="1;width:100%; height:200px;style=text-align:center" | |
| - | Physical Property | + | |+'''Physiochemical properties of Estriol:''' |
| + | |- | ||
| + | ! style="background:brown; color:white" |Physical Property | ||
| + | ! style="background:brown; color:white" |Value | ||
| + | ! style="background:brown; color:white" |Units | ||
| + | ! style="background:brown; color:white" |Temp (deg C) | ||
| + | ! style="background:brown; color:white" |Source | ||
| + | |- | ||
|Melting Point | |Melting Point | ||
|200 | |200 | ||
Revision as of 11:34, 31 October 2008
3,20-Allopregnanedione Pubchem(92810)
A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR.
KEGG Pathway(C03681) C21-Steroid hormone metabolism
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 200 | deg C | EXP | |
| log P (octanol-water) | 3.460 | (none) | EST | |
| Atmospheric OH Rate Constant | 3.85E-11 | cm3/molecule-sec | 25 | EST |
| mouse | LDLo | intraperitoneal | 80mg/kg (80mg/kg) | Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |
| mouse | LDLo | intravenous | 10mg/kg (10mg/kg) | Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |
