5alpha-Dihydroprogesterone
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(New page: 3,20-Allopregnanedione Pubchem(92810) A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREG...)
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Revision as of 11:34, 31 October 2008
3,20-Allopregnanedione Pubchem(92810)
A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR.
KEGG Pathway(C03681) C21-Steroid hormone metabolism
Physical Property Value Units Temp (deg C) Source |Melting Point |200 |deg C | |EXP |- |log P (octanol-water) |3.460 |(none) | |EST |- |Atmospheric OH Rate Constant |3.85E-11 |cm3/molecule-sec |25 |EST |-
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source |mouse |LDLo |intraperitoneal |80mg/kg (80mg/kg) |Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |- |mouse |LDLo |intravenous |10mg/kg (10mg/kg) |Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |-
