PolysacDB Fibrinolysin glycoprotein 2572

From DrugPedia: A Wikipedia for Drug discovery

---

Revision as of 06:14, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Fibrinolysin glycoprotein

Carbohydrate Class

Miscellaneous

Source Microbe

Yersinia pestis

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Purified fibrinolysin

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab E

Antibody type and class

IgG1

Assay System

indirect immunofluorescence, ELISA, immunoblotting and reaction of Fib-activity inhibition

Cross-reactivity

This Mab was specific to Y. pestis. This Mab also reacted with Y. pestis LPS

Proposed epitopes

The carbohydrate part of Fibrinolysin protein was a Y. pestis cell-wall fragment, not a subunit of the complex molecule

Proposed Utility

This Mab can be used for immunodetection of Y. pestis in plaques

Weblink

PubMed

External Links

• Link to PolysacDB database