Pregnenolone

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(New page: '''Pregnenolone''' Pubchem(8955) A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES a...)
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Revision as of 05:43, 31 October 2008

Pregnenolone

Pubchem(8955)

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.

Drug Type: Small Molecule; Experimental

KEGG Pathway(C01953,D00143)

  • C21-Steroid hormone metabolism

Physical Property Value Units Temp (deg C) Source |Melting Point |192 |deg C | |EXP |- |log P (octanol-water) |4.22 |(none) | |EXP |- |Water Solubility |7.06 |mg/L |37 |EXP |- |Vapor Pressure |1.03E-08 |mm Hg |25 |EST |- |Henry's Law Constant |1.17E-08 |atm-m3/mole |25 |EST |- |Atmospheric OH Rate Constant |1.20E-10 |cm3/molecule-sec |25 |EST |- |} Organism Test Type Route Reported Dose (Normalized Dose) Effect Source |mouse |LD |intraperitoneal |> 200mg/kg (200mg/kg) | |Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |- |}