PolysacDB Lipopolysaccharide 2454
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Revision as of 06:13, 8 April 2010
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Shigella flexneri serotype X
Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1-
Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodies
Phenol killed cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab X-15
Antibody type and class
IgG3
Assay System
ELISA, immunodiffusion
Cross-reactivity
This Mab cross-reacted with 3a LPS
Proposed epitopes
This Mab reacted with alkali-treated LPS and O-antigen
Proposed Utility
This Mab can be used for antigenic characterization of Shigella LPS
