PolysacDB Capsular polysaccharide 2424

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Revision as of 06:13, 8 April 2010


Contents

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Streptococcus Group B

Basic Structure

The structure of type III polysaccharide is as follows : -3-β-D-Galp-(1-->4)-β-D-Glcp-(1-->6)-β-D-GlcNAcp-(1--> along with the fact that the carboxyl of the -D-NeuNAcp was linked to the O-3 of the adjacent D-galactose to form the type-specific site


Proposed functions

The property of invasiveness is related to the anti-phagocytic properties conferred to Group B Streptococcus by its capsular polysaccharide

Antigenic Nature used to produce antibodies

Formalin treated cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab GBS III/3-5AC8

Antibody type and class

N/A

Assay System

Counterimmunoelectrophoresis, Radioactive binding assay, Ouchterlony double-diffusion, Latex particle agglutination tests

Cross-reactivity

C8 antibody cross-reacted with group B antigen in gel diffusion reactions with extracts of Lancefield group A, B, C, D, F, and G streptococci

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed Central

External Links