PolysacDB Exopolysaccharide 2344

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 06:13, 8 April 2010 (edit) Raghavagps (Talk | contribs) m (1 revision) ← Previous diff

Current revision (05:53, 9 September 2010) (edit) (undo) Raghavagps (Talk | contribs) m (1 revision)

---

Current revision

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Exopolysaccharide

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Shewanella colweliana

[edit] Basic Structure

The EPS is composed of mannose, glucose, galactose, and pyruvate in a 1:2:2:4 molar ratio. Molecular weight analysis by gel filtration demonstrates that the EPS is polydispersive and composed of a major high-molecularweight species and lesser amounts of smaller molecularweight species

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab Aco6

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA, Immunofluorescence and immunoblotting

[edit] Cross-reactivity

This Mab was specific to EPS of Shwenella colweliana

[edit] Proposed epitopes

This EPS epitope was sensitive to cleavage of ester bonds, but neither pyruvate, acetate, nor terminal nonreducing sugars were required for antigenicity

[edit] Proposed Utility

This Mab can be used to quantitate the synthesis and probe the function of S. colwelliana EPS

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database