PolysacDB Core oligosaccharide 2318
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Revision as of 06:13, 8 April 2010
Carbohydrate Name
Core oligosaccharide
Carbohydrate Class
Core oligosaccharide [LPS]
Source Microbe
Shigella flexneri serotype 1b
Basic Structure
The core is a single sequence of heptoses and hexoses
Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodies
Heat killed cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab MASF R3 core-1
Antibody type and class
IgG2a
Assay System
immunoblotting, enzyme-linked immunosorbent assay (ELISA), hemagglutination, and coagglutination
Cross-reactivity
The core-specific antibodies were shown to be specific for the Escherichia coli R3 core, which all S. flexneri LPSs were found to have, except for S. flexneri serotype 6 LPS
Proposed epitopes
N/A
Proposed Utility
This Mab can be used for detection and identification of shigella flexneri species
