PolysacDB Y O-polysaccharide 2268
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Revision as of 06:13, 8 April 2010
Carbohydrate Name
Y O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Shigella flexneri
Basic Structure
The O-LPS consists of a tetrasaccharide repeating unit α-L-Rhap-(1-->2)-α-L-Rhap(1-->3)- . This tetrasaccharide is polymerized and joined by β-1,2 linkages between N-acetyl-D-glucosamine and L-rhamnosyl to form the O-polysaccharide chain
Proposed functions
N/A
Antigenic Nature used to produce antibodies
heat-killed S. flexnerf bacteria serotype Y
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab MASF Y-4
Antibody type and class
N/A
Assay System
ELISA, FARR assay
Cross-reactivity
MASF Y-4 bound to LPS of serotypes 2a. 3b, 4a, 4b, 5a, and Y
Proposed epitopes
the terminal nonreducing end of the O-polysaccharide complementary to the tetrasaccharide repeating unit
Proposed Utility
This Mab would help in the delineation of the antigenic stucture of Y O polysaccharide
