PolysacDB Lipopolysaccharide 2210

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Salmonella minnesota Re chemotype 595

[edit] Basic Structure

LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo

[edit] Proposed functions

LPS plays an important virulence role based on its antiphagocytic and endotoxic properties

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab E1

[edit] Antibody type and class

IgG3

[edit] Assay System

direct and inhibition enzyme immunoassays

[edit] Cross-reactivity

MAb E1 reacted exclusively with those of Re-chemotype

[edit] Proposed epitopes

It recognized α-Kdo- monosaccharide and disaccharide structures present as non-reducing side chains in various Re-type LPSs and synthetic antigens

[edit] Proposed Utility

This Mab can be used for identification of Salmonella strains having the Re chemotype

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database