Tipepidine citrate
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Revision as of 08:01, 24 October 2008
Tipepidine (Bithiodine, Sotal, Antupex, Asverin) is a centrally-acting cough suppressant of the opioid type. It is a member of the thiambutene series of open-chain (methadone-related) synthetic opioids, which include Ohton (dimethylthiambutene), a strong narcotic analgesic used particularly in veterinary medicine in Japan and other East Asian countries. It was developed in Japan in 1959 and is used as the citrate and hibenzate salts. The usual dose is 20 mg every 4–6 hours. Its relative weakness and other properties make it a drug which is not controlled in most countries or internationally.
Synonyms
Tipepidine citrate Tipepidine citrate (JAN) D02023 14698-07-8
Properties
| Molecular Weight | 467.5557 [g/mol] |
| Molecular Formula | C21H25NO7S2 |
| H-Bond Donor | 4 |
| H-Bond Acceptor | 8 |
| Rotatable Bond Count | 7 |
| Exact Mass | 467.107244 |
| MonoIsotopic Mass | 467.107244 |
| Topological Polar Surface Area | 135 |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 536 |
| Isotope Atom Count | 0 |
| Defined Atom StereoCenter Count | 0 |
| Undefined Atom StereoCenter Count | 0 |
| Defined Bond StereoCenter Count | 0 |
| Undefined Bond StereoCenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
