PolysacDB Lipopolysaccharide 1879

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Revision as of 06:10, 8 April 2010


Contents

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Neisseria meningitidis group A strain 4402

Basic Structure

It consists of a homopolymer of α(2-->8)-linked sialic acid residues


Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MCA14.2

Antibody type and class

N/A

Assay System

coagglutination, enzyme-linked immunosorbent assay and immunoblotting

Cross-reactivity

This Mab cross-reacted with a group A strain having the L10 serotype and a group B meningococcal strain and Haemophilus influenzae type B, but not with the lipopolysaccharides of several strains of Salmonella typhi, Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed Central

External Links