PolysacDB Lipopolysaccharide 1879
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(Difference between revisions)
Revision as of 06:10, 8 April 2010
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Neisseria meningitidis group A strain 4402
Basic Structure
It consists of a homopolymer of α(2-->8)-linked sialic acid residues
Proposed functions
It is an important virulence factor
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab MCA14.2
Antibody type and class
N/A
Assay System
coagglutination, enzyme-linked immunosorbent assay and immunoblotting
Cross-reactivity
This Mab cross-reacted with a group A strain having the L10 serotype and a group B meningococcal strain and Haemophilus influenzae type B, but not with the lipopolysaccharides of several strains of Salmonella typhi, Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae
Proposed epitopes
N/A
Proposed Utility
N/A