PolysacDB Capsular polysaccharide 1871

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Revision as of 06:10, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Neisseria meningitidis group B

Basic Structure

It consists of a homopolymer of α(2-->8)-linked sialic acid residues

Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

tonsillar B cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 5E1

Antibody type and class

IgM

Assay System

ELISA

Cross-reactivity

This Mab reacts with E. coli K1 polysaccharide

Proposed epitopes

N/A

Proposed Utility

This antibody protected infant rats from bacteremia caused by Escherichia coli K1

Weblink

PubMed

External Links

• BCSDB Structural Detail

• Link to PolysacDB database