PolysacDB Lipopolysaccharide 1785

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Current revision (05:51, 9 September 2010) (edit) (undo) Raghavagps (Talk | contribs) m (1 revision)

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Myxococcus xanthus

[edit] Basic Structure

It consists of Lipid A region covalently linked to the core region

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 1514

[edit] Antibody type and class

IgG2a

[edit] Assay System

ELISA, immunoblotting

[edit] Cross-reactivity

This Mab was specific to M. xanthus and did not bind to LPS of any other gram negative bacteria

[edit] Proposed epitopes

O-antigen of the LPS seems to constitute the epitope

[edit] Proposed Utility

This MAb may be a useful probe for detecting specific alterations in the LPS structure which may occur during the development of M. xanthus. This Mab has been used to isolate many LPS biosynthesis mutants

[edit] Weblink

PubMed Central

[edit] External Links

• BCSDB Structural Detail

• Link to PolysacDB database