PolysacDB Arabinogalactan and arabinomannan 1744
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Revision as of 06:09, 8 April 2010
Carbohydrate Name
Arabinogalactan and arabinomannan
Carbohydrate Class
Miscellaneous
Source Microbe
Mycobacterium tuberculosis
Basic Structure
Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues, and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
Proposed functions
N/A
Antigenic Nature used to produce antibodies
M. tuberculosis culture filtrate
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab TB-C-1
Antibody type and class
IgM
Assay System
ELISA, immunoblotting, Immunosorbent affinity chromatography and Immunoelectrophoresis
Cross-reactivity
This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare
Proposed epitopes
N/A
Proposed Utility
This Mab would allow the purification of important mycobacterial antigens antigens
