PolysacDB Unknown carbohydrate 1543
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[edit] Carbohydrate Name
Unknown carbohydrate
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Leishmania tropica (LRC-L137)
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
L. tropica (LRC-L137) promastigotes
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab L-5-41
[edit] Antibody type and class
IgG2b
[edit] Assay System
solid-phase radioimmunoassay, Indirect fluorescent antibody test
[edit] Cross-reactivity
This Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It did not cross-react with any other Leishmania species
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab abolished capacity of the pathogen to multiply within macrophages in vitro and indeed promoted parasite killing