PolysacDB Capsular polysaccharide 1508

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Revision as of 06:08, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Actinobacillus pleuropneumoniae serotype b strain 81-750

Basic Structure

Consists of a common backbone consisting of disaccharide repeating units, [->6)-α-DGlcpNAc (1-->5)-β-Kdop-(2-->]n, but, in addition, the CPS of serotype 5b has a lateral β-D glucopyranosyl residue

Proposed functions

N/A

Antigenic Nature used to produce antibodies

formaldehyde killed cells and 2 injections with tetanus toxoid CPS strain L20 conjugate (CPS L20-TT)

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 2B4

Antibody type and class

IgM

Assay System

ELISA and dot ELISA

Cross-reactivity

This antibody cross-reacted strongly with LPS of serotype 5b

Proposed epitopes

N/A

Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

Weblink

PubMed Central

External Links

• Link to PolysacDB database