PolysacDB Mannan 1345

From DrugPedia: A Wikipedia for Drug discovery

---

Revision as of 06:04, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Mannan

Carbohydrate Class

Miscellaneous

Source Microbe

Candida albicans NIH A-207

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Polyclonal Antisera

Antibody type and class

N/A

Assay System

Ouchterlony double immunodiffusion

Cross-reactivity

The antisera did not cross-react with C. albicans NIH B-792 but cross-reracted with Hormodendrum strains, H. pedrosoi IFO 6071, H. compactum IFO 6726, and H. dermatitidis IFO 6421

Proposed epitopes

The epitope was proposed to consist of α-D-mannopyranosyl residues occupying the nonreducing terminals of the branching moieties

Proposed Utility

This antisera was used to study the structural similarities between Candida mannans and Hormemendrum galactomannans

Weblink

PubMed Central

External Links

• IEDB Epitopic Detail

• Link to PolysacDB database