PolysacDB Glycan fraction 1328

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 06:04, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Glycan fraction

Carbohydrate Class

Miscellaneous

Source Microbe

Candida albicans B311

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 4G8

Antibody type and class

IgM

Assay System

ELISA, immunofluorescence, crossed immunoelectrophoresis

Cross-reactivity

This antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia and S. cerevisae but did not cross-react with T. glabrata

Proposed epitopes

N/A

Proposed Utility

This Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays

Weblink

PubMed Central

External Links

• Link to PolysacDB database