PolysacDB O-polysaccharide 1261
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Revision as of 06:03, 8 April 2010
Carbohydrate Name
O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Campylobacter fetus 554
Basic Structure
The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)
Proposed functions
The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme
Antigenic Nature used to produce antibodies
a mixture (1:1) of C. fetus 553 and 554 formalin-killed cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Mab M1183
Antibody type and class
IgG1
Assay System
Indirect ELISA, immunoblotting,
Cross-reactivity
This antibody was specific to O antigen of C. fetus 553 and did not cross-react with C. fetus 554
Proposed epitopes
N/A
Proposed Utility
This Mab can be used to serotype C. fetus strains
