PolysacDB Polysaccharide B 1154

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 06:03, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Polysaccharide B

Carbohydrate Class

Miscellaneous

Source Microbe

Bacteroides fragilis NCTC 9344

Basic Structure

It contained fucose (15%), galactose (23%), quinovosamine (27%), and glucosamine (23%)

Proposed functions

This forms a part of the capsular polysaccharide of B. fragilis which is an important virulence factor

Antigenic Nature used to produce antibodies

formalin-killed whole B. fragilis cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab F10

Antibody type and class

IgG2a

Assay System

Immunoblotting, immunofluorescence

Cross-reactivity

N/A

Proposed epitopes

N/A

Proposed Utility

This Mab may help in the elucidation of variability of surface polysaccharide structures

Weblink

PubMed Central

External Links

• Link to PolysacDB database