PolysacDB O-polysaccharide 1122
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Revision as of 06:03, 8 April 2010
Carbohydrate Name
O-polysaccharide
Carbohydrate Class
O-polysaccharide [LPS]
Source Microbe
Actinobacillus pleuropneumoniae serotype 1
Basic Structure
O chains of LPS of are composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone
Proposed functions
LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
Antigenic Nature used to produce antibodies
formalin-fixed A. pleuropneumoniae serotype 1 cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Polysera
Antibody type and class
N/A
Assay System
ELISA
Cross-reactivity
This antibody cross-reacted with serotypes 9 and 11
Proposed epitopes
The epitope was deduced to contain the terminal nonreducing -D-Glc NAc residues
Proposed Utility
This antisera not only helped in serotyping analysis but also helped in deducing the epitopes recognized
