Dictyostelium discoideum

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	'''Dictyostelium discoideum'''		'''Dictyostelium discoideum'''
		+	It is a species of soil-living amoeba belonging to the phylum Mycetozoa. D. discoideum, commonly referred to as slime mold, is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its life time. D. discoideum has a unique asexual lifecycle that consists of four stages: vegetative, aggregation, migration, and culmination.
		+	{| border="1" style="text-align: left;"
		+	|+ '''Scientific classification'''
		+	! Division || Eukarya
		+	|-
		+	!Kingdom || Amoebozoa
		+	|-
		+	! Phylum || Mycetozoa
		+	|-
		+	! Class || Dictyostelia
		+	|-
		+	! Order || Dictyosteliida
		+	|-
		+	! Family || Dictyosteliidae
		+	|-
		+	! Genus || Dictyostelium
		+	|-
		+	! Species || '''''D. discoideum'''''
		+	|-
		+	! Binomial || ''Dictyostelium discoideum''
		+	|}
		+	==Pathogenic Activity==
		+	These slime molds are used to test anti-cancer drugs, immune-cell diseases, and bacterial intracellular pathogenesis. Also, recently it was established that Dictyostelium use DNA methylation for regulating gene expression.
		+	Individual cell behavior accounts for many phases of health and disease. This is portrayed in D. discoideum in many different ways. Cytokinesis acts as part of immune response, tissue maintenance, and cancer, in the form of cell proliferation. Chemotaxis deals with inflammation, arthritis, asthma, lymphocyte trafficking, and axon guidance. Phagocytosis is used in immune surveillance and antigen presentation, while cell-type determination, cell sorting, and pattern formation are basic features of embryogenesis.
		+
		+	Legionella is a genus of bacteria that includes species that can cause Legionnaire's disease in humans. D. discoideum is also a host for Legionella and is a suitable model for studying the infection process. Specifically, D. discoideum shares with mammalian host cells a similar cytoskeleton and cellular processes relevant to Legionella infection, including phagocytosis, membrane trafficking, endocytosis, vesicle sorting, and chemotaxis.
		+
		+	==References==
		+	[http://en.wikipedia.org/wiki/Dictyostelium_discoideum Wikipedia]
	[[category: CarboDB]]		[[category: CarboDB]]

---

Revision as of 06:01, 13 July 2010

Dictyostelium discoideum

It is a species of soil-living amoeba belonging to the phylum Mycetozoa. D. discoideum, commonly referred to as slime mold, is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its life time. D. discoideum has a unique asexual lifecycle that consists of four stages: vegetative, aggregation, migration, and culmination.

Scientific classification

Division	Eukarya
Kingdom	Amoebozoa
Phylum	Mycetozoa
Class	Dictyostelia
Order	Dictyosteliida
Family	Dictyosteliidae
Genus	Dictyostelium
Species	D. discoideum
Binomial	Dictyostelium discoideum

Pathogenic Activity

These slime molds are used to test anti-cancer drugs, immune-cell diseases, and bacterial intracellular pathogenesis. Also, recently it was established that Dictyostelium use DNA methylation for regulating gene expression.

Individual cell behavior accounts for many phases of health and disease. This is portrayed in D. discoideum in many different ways. Cytokinesis acts as part of immune response, tissue maintenance, and cancer, in the form of cell proliferation. Chemotaxis deals with inflammation, arthritis, asthma, lymphocyte trafficking, and axon guidance. Phagocytosis is used in immune surveillance and antigen presentation, while cell-type determination, cell sorting, and pattern formation are basic features of embryogenesis.

Legionella is a genus of bacteria that includes species that can cause Legionnaire's disease in humans. D. discoideum is also a host for Legionella and is a suitable model for studying the infection process. Specifically, D. discoideum shares with mammalian host cells a similar cytoskeleton and cellular processes relevant to Legionella infection, including phagocytosis, membrane trafficking, endocytosis, vesicle sorting, and chemotaxis.

References

Wikipedia