CarboDB Exopolysaccharide 2342

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Exopolysaccharide

Carbohydrate Class

Miscellaneous

Source Microbe

Shewanella colweliana

Basic Structure

The EPS is composed of mannose, glucose, galactose, and pyruvate in a 1:2:2:4 molar ratio. Molecular weight analysis by gel filtration demonstrates that the EPS is polydispersive and composed of a major high-molecularweight species and lesser amounts of smaller molecularweight species

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Aco4

Antibody type and class

IgG2b

Assay System

ELISA, Immunofluorescence and immunoblotting

Cross-reactivity

This Mab was specific to EPS of Shwenella colweliana

Proposed epitopes

This EPS epitope was sensitive to cleavage of ester bonds, but neither pyruvate, acetate, nor terminal nonreducing sugars were required for antigenicity

Proposed Utility

This Mab can be used to quantitate the synthesis and probe the function of S. colwelliana EPS

Weblink

PubMed

External Links

• Link to CarboDB database