CarboDB O-polysaccharide 2164

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

O-polysaccharide

Carbohydrate Class

O-polysaccharide [LPS]

Source Microbe

Pseudomonas aeruginosa Serotype O14

Basic Structure

The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Formalin killed whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab MF45-4

Antibody type and class

N/A

Assay System

ELISA, immunoblotting and Double immunodiffusion

Cross-reactivity

This Mab was specific to its homologous serotype

Proposed epitopes

N/A

Proposed Utility

This Mab can be used for serotyping of Pseudomonas aeruginosa strains

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• Link to CarboDB database