CarboDB Cell surface polysaccharide alginate 2053

From DrugPedia: A Wikipedia for Drug discovery

---

Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

cell surface polysaccharide alginate

Carbohydrate Class

Miscellaneous

Source Microbe

Pseudomonas aeruginosa

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Purified alginate

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab F429

Antibody type and class

IgG1

Assay System

ELISA and protection assays

Cross-reactivity

N/A

Proposed epitopes

intact carboxylate groups on the C6 carbon of the mannuronic acid residues

Proposed Utility

This Mab was found to promote phagocytic killing of both mucoid and nonmucoid strains as well as conferred protection against both types of strains in a mouse model of acute pneumonia

Weblink

PubMed

External Links

• Link to CarboDB database