CarboDB Capsular polysaccharide 1882

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Capsular polysaccharide

Carbohydrate Class

Capsular polysaccharide

Source Microbe

Neisseria meningitidis group A strain A1

Basic Structure

It consists of a homopolymer of α(2-->8)-linked sialic acid residues

Proposed functions

It is an important virulence factor

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 4387A5

Antibody type and class

IgG2a

Assay System

ELISA, immunodot assay, and ELISA inhibition assay

Cross-reactivity

This Mab was highly specific to A1 lipooligosaccharide but also cross-reacted with L8 lipooligosaccharide

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed Central

External Links

• Link to CarboDB database