CarboDB Antigen 5 1753

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Antigen 5

Carbohydrate Class

Miscellaneous

Source Microbe

Mycobacterium tuberculosis

Basic Structure

Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis

Proposed functions

N/A

Antigenic Nature used to produce antibodies

M. tuberculosis culture filtrate

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab TB-C-8

Antibody type and class

IgM

Assay System

ELISA, immunoabsorbent affinity chromatography

Cross-reactivity

This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis

Proposed epitopes

Arabinomannan and arabinogalactan residues seemed to be a part of the epitope

Proposed Utility

This Mab would allow the purification of important mycobacterial antigens antigens

Weblink

PubMed Central

External Links

• Link to CarboDB database