CarboDB Lipopolysaccharide 1473

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Helicobacter pylori

Basic Structure

The structure of the O-polysaccharide part of the LPS is the same as the Lewis X (Lex) and Lewis Y (Ley) determinants of the human cell surface glycoconjugates

Proposed functions

The O-polysaccharide regions of these LPS were found to be a major antigenic determinant

Antigenic Nature used to produce antibodies

N/A

Carrier Name

N/A

Conjugation Method

N/A

Antibodies

Mab BG-7 (P12)

Antibody type and class

IgM

Assay System

Immunoblotting and ELISA

Cross-reactivity

This anti-Lex Mab reacted with strains DU1, DU2, GU2 and CA6, GU9 and CA4 and did not react with strains 43504-r and CG7

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed Central

External Links

• BCSDB Structural Detail

• IEDB Epitopic Detail

• Link to CarboDB database