CarboDB Lipopolysaccharide 1460
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001
Carbohydrate Name
Lipopolysaccharide
Carbohydrate Class
Lipopolysaccharide
Source Microbe
Haemophilus ducreyi CCUG 4438
Basic Structure
It consist of an oligosaccharide core ketosidically linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to the lipid A region. The oligosaccharide core characteristic of these bacteria has been divided into two regions: (i) an inner core, consisting of three L-glycero-D-manno-heptose (Hep) residues and one phosphorylated Kdo residue, and (ii) an outer core, with one or more heterogeneous oligosaccharide branches containing mainly galactose (Gal) and glucose (Glc) residues
Proposed functions
LPS plays an important role in the infection process
Antigenic Nature used to produce antibodies
Whole cells
Carrier Name
nil
Conjugation Method
nil
Antibodies
Polysera
Antibody type and class
N/A
Assay System
ELISA and immunoblotting
Cross-reactivity
the antiserum to CCUG 4438 reacted with only its homologous strain and strain ITM 4747
Proposed epitopes
N/A
Proposed Utility
This antisera would aid in the classification of H. ducreyi for epidemiological purposes
